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Abstract

Review Article

Concise Review: Considerations for the Formulation, Delivery and Administration Routes of Biopharmaceuticals

Amir Mohammed Alsharabasy*

Published: 28 June, 2017 | Volume 1 - Issue 1 | Pages: 033-053

The drugs of biological origins have attracted the attention of many pharmaceutical companies where it is essential to protect the heterogeneous nature and the optimal three dimensional structures of the different macromolecules. These molecules are used in both the investigation and therapy purposes, so their maximum activities should be maintained. This requires the designing of certain delivery formulations that suits the macromolecule nature, its target organ, the required dose and delivery route, and that’s why the biotech companies invest millions of dollars towards achieving that. The first main focal point of this article includes the recent developments in the formulation technologies for several biomacromolecule classes. The second focal point concentrates on the current considerations for optimizing their delivery for a maximum performance in the body.

Read Full Article HTML DOI: 10.29328/journal.hjb.1001004 Cite this Article Read Full Article PDF

Keywords:

Biopharmaceutical; Drug formulation; Delivery; Administration routes

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Assaf Harofeh Medical Center, Israel

Leonid Feldman

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Yvonne Mast

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Dr. Elizabeth A Awoyesuku

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Ayokunle Dada

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Ido-Ekiti/Afe Babalola University, Nigeria

Dr. Shuaib Kayode Aremu

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Ekiti State University, Nigeria

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Atsedemariam Andualem

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Palestine College of Nursing, Khan Younis, Gaza Strip, Palestine

Ayman M Abu Mustafa

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Department of Agricultural Economics, Agribusiness and Extension, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

Akowuah Jones Asafo

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