Figure 9

OPEN and CLOSED state of SPIKE SARS-COV-2: relationship with some integrin binding. A biological molecular approach to better understand the coagulant effect

Luisetto M*, Khaled Edbey, Mashori GR, Yesvi AR and Latyschev OY

Published: 02 July, 2021 | Volume 5 - Issue 1 | Pages: 049-056

abb-aid1028-g009

Figure 9:

9: Scanning electron- micrographs of healthy control whole- blood (WB), with and without spike protein. A and B) Healthy WB smears, with arrows indicating normal erythrocyte- ultrastructure. C to H) Healthy WB exposed to spike- protein (1 ng.mL-1 final concentration), with C and D) indicating the activated -platelets (arrow), E and F) showing the spontaneously formed fibrin- network and G and H) the anomalous deposits that is amyloid in nature (arrows) (Scale bars: E: 20μm; A: 10μm; F and G: 5μm; H: 2μm; C: 1μm; B and D: 500nm). Form article SARS-CoV-2 spike S1 subunit induces hyper-coagulability SARS-CoV-2 spike protein S1 induces fibrin (ogen) resistant to the fibrinolysis: Implications for microclot formation in COVID-19 Lize M. Grobbelaar, Chantelle Venter, Mare Vlok, Malebogo Ngoepe, Gert Jacobus Laubscher, Petrus Johannes Lourens, Janami Steenkamp Douglas B. Kell, Etheresia Pretorius Preprint. Wool GD, Miller JL. The Impact of COVID-19 Disease on Platelets and Coagulation Pathobiology 2021; 88: 15–27.

Read Full Article HTML DOI: 10.29328/journal.abb.1001028 Cite this Article Read Full Article PDF

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